The Research

The research that eventually evolved into Potentiated Magnesium (pMg) first began in 1968 when an independent orthomolecular biochemistry researcher was searching for a natural remedy for stress-induced premature ventricular contractions (PVCs), a type of irregular heartbeat that is usually perceived as a skipped heartbeat and is caused by physical, mental or emotional stress (absent an underlying organic cause).  After researching every single known nutrient, one at a time, the focus was narrowed to minerals, which, after about a dozen years of trial and error, eventually led to the essential mineral magnesium.  It took about another 10 years or so to develop a way that would overcome magnesium’s inherent hydrophilic nature (magnesium’s Achilles’ heel), which eventually evolved into the Compound Complex process.

In 1991 The Research Lab was founded as a dedicated Research and Development (R&D) entity, as the research intensified.  During the 1990’s it was learned just how important and powerful the essential mineral magnesium really is – once it could be taken in meaningful amounts without it producing its usual laxative side effect – thanks to the development of the unique Compound Complex process.  This revealed the extraordinary health benefits potential of magnesium – the potential it always had but previously went unrecognized simply because not enough could be taken – which eventually far eclipsed its ability to help control stress-induced PVCs.

Several of the early research studies demonstrated that as much as 3,000 mg per day of elemental magnesium from pMg could be taken on an ongoing basis for at least a year, and 1,700 mg to 2,300 mg taken for more than 10 years – without producing a laxative effect or any deleterious side effects.  These intake amounts of magnesium were previously unheard of, and virtually impossible to take with any other kind of oral magnesium supplement.  From then on, numerous research studies were conducted and several patents applied for.

Four of the most important things to come out of the research was: (1) The discovery of the underlying cause of dystrophic calcification (which is unbalanced calcium metabolism); (2) The discovery of the formation pathway of dystrophic calcification; (3) How the essential mineral magnesium balances calcium metabolism; and (4) The profound beneficial impact of the adequate intake of magnesium and vitamin C has on the support, structural integrity, and normal function of the cardiovascular system. 

The Key to Magnesium’s Effectiveness

The key to magnesium’s effectiveness is that it is a natural calcium channel blocker that regulates and controls how much potential cell-damaging calcium is allowed to enter cells, thus being the only thing that can balance calcium metabolism.  And, the only form of magnesium that has demonstrated its ability to effectively balance calcium metabolism, by allowing optimum amounts to be consumed without producing magnesium’s usual inherent hydrophilic laxative effect or any other deleterious side effect, is Potentiated Magnesium (pMg).

Potentiated Magnesium has had more research conducted with it, over a longer period of time, than any other dietary supplement in history before making it available to the commercial marketplace, and is the most important development in dietary supplements since dietary supplements have been in existence.  The most powerful and effective magnesium ever developed is Potentiated Magnesium.

The Most Important Discoveries & Developments

Unbalanced Calcium Metabolism – Unbalanced calcium metabolism is the underlying cause of dystrophic calcification (calcium deposits in soft tissues).  (See “Unbalanced Calcium Metabolism” for more details.)

Dystrophic Calcification Pathway – The sequential, cascading, physiological pathway of dystrophic calcification and its connection to unbalanced calcium metabolism and inadequate magnesium intake.

Heart Health & Health Span – The basis of health, especially heart health, includes: (1) Proper Nutrition, (2) Regular Exercise, (3) Adequate Sleep, (4) Stress Management, and (5) An adequate intake of Vital Nutrients.  (See “The Five Pillars of Health” for more details.)

Compound Complex – The unique way in which Potentiated Magnesium (pMg) is produced is the result of a newly developed and patented process that, for the first time in the history of magnesium supplements, successfully overcomes magnesium’s inherent hydrophilic nature, and in so doing imparts a supercharged synergy between the ingredients.  It is the Compound Complex process of pMg that allows its unprecedented maximum intestinal absorption and optimum cellular utilization.  (See “The Key To pMg’s Effectiveness” and “Compound Complex & Maxcelint Uptake” for more details.)

Potentiated Magnesium – Potentiated Magnesium (pMg) provides unparalleled support for the normal function of the cardiovascular system, circulation, respiratory system, cellular function, energy production, muscle function, and Health Span support.

Potentiated Magnesium is the only substance, natural or otherwise, that has demonstrated (in its worlwide patents) the reversal of the dystrophic calcification process and reduced its physical presence.  (Reference the following Patents: U.S. 5,849,337, U.S. 6,372,264, Canada 2,295,108, Japan 3622985, China ZL 02828726.6, and the European Union EP 1003370 encompassing France, Germany, and the United Kingdom.)  (See “Potentiated Magnesium” for more detailed information.)

Go To The MAX – Potentiated Magnesium plus Zinc (MAX) provides unparalleled support for the normal function muscles (skeletal and cardio), and naturally supports muscle strength, endurance, power, peak physical performance, aerobic capacity (VO₂ max), workout recovery, energy production, and supports the normal function of the immune system.  It has been demonstrated in several independent research studies that the right balance of the essential mineral magnesium with just the right amount of the essential mineral zinc supports natural muscle strength gains (from 11% up to 56%) when taken at bedtime after engaging in exercise or physical activity earlier in the day.  (Reference: Journal of Nutrition 132: 930-935 2002; American Journal of Clinical Nutrition 72: #2, 585s-593s 2000; Medicine and Science in Sports & Exercise 31: #5, 483 1999; Journal of The American College of Nutrition 11: 326-329 1992; Am Journal of Clinical Nutrition 49: 1295-1301 1989; Journal of Applied Physiology 62: 545-550 1987; Am Journal of Clinical Nutrition 37: 407-415 1983)  (See “Go To The MAX” for more detailed information.)

The Science

The science behind Potentiated Magnesium (pMg) is the relatively new science of Orthomolecular Biochemistry Research, which is the study of nutrients and what they do on the cellular and molecular level within the biochemistry of the living human body.

The late, great Dr. Linus Pauling is considered the father of this science, with him first coining the term “orthomolecular,” which was often stated by him as “orthomolecular medicine.”  Michael W. Dixon, the independent orthomolecular biochemistry researcher who followed the basic teachings of Dr. Linus Pauling (and later expanded on them), and who is the founder and director of The Research Lab (the entity that developed pMg, conducted the research studies, and acquired all the patents on pMg), and the founder and director of Maxcelint Laboratories Inc. (the exclusive producer of pMg), first coined the term “Orthomolecular Biochemistry Research” – thus giving a name to this important science.  The study of how nutrients and phytochemicals work within the human body – on the cellular and molecular level – is serious science.

It is through orthomolecular biochemistry research that all the great discoveries are made, and are likely to continue to be made, that may provide us with the natural remedies for some of the worst health conditions that affect mankind.  Without orthomolecular biochemistry research we wouldn’t know about omega-3s, CoQ10, the newly discovered benefits of vitamin D – and perhaps the most important discovery and development of our time: Potentiated Magnesium.

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The Patents

Potentiated Magnesium (pMg) has had more patents actually issued (not just patents pending) than any other dietary supplement.  And, quite importantly, has the only patents ever issued for a dietary supplement that specifically does what pMg does within the human body – namely:

1. Enhanced Uptake – Maximum GI tract absorption and optimum cellular utilization;

2. No Laxative Effect – Overcomes magnesium’s inherent hydrophilic nature;

3. Balances Calcium Metabolism – Has demonstrated prevention of dystrophic calcification and cellular damage by balancing calcium metabolism;

4. Dystrophic Calcification Reversal and Reduction – Has demonstrated reversal of the dystrophic calcification process and reduction of the physical presence of dystrophic calcification by balancing calcium metabolism;

5. Compound Complex – Developed unique dietary supplement formation process that imparts an enhanced synergy between the nutrients, which maximizes each nutrient’s power and effectiveness.

These aspects of the patents are a first in U.S. and world patent history for a dietary supplement.

The U.S. Patents for Potentiated Magnesium (pMg) detail the enhanced uptake, health support, and research studies of pMg, and include “before” and “after” electron-beam CT heart scans.

The U.S. Patents

U.S. Patent No. 5,849,337 (titled: “Method of Enhancing Magnesium Absorption…”).

U.S. Patent No. 6,372,264 (titled: “Method of Reducing…Cellular Malfunction and For Balancing Ionic Calcium”).

The International Patents

Potentiated Magnesium is also patented in several other countries around the world: Canada 2,295,108, Japan 3622985, China ZL 02828726.6, and the European Union EP 1003370, which includes the countries of France, Germany, and the United Kingdom.  Like the U.S. Patents, these International Patents have all been issued by their respective countries (rather than just being “patent pending”).

Even though Potentiated Magnesium may eventually be offered for sale in other countries, it will continue to be produced only in the U.S.A.  Even though Potentiated Magnesium may one day be licensed and offered under other label brands, it will continue to be produced exclusively by Maxcelint Laboratories Inc. and certified in the U.S.A.

U.S. Patent Abstracts

A patent abstract is basically a summary of the patent.

U.S. Patent No. 5,849,337 abstract (in part):

“A method for making and administering a compounded coordination complex of magnesium that enhances the biological absorption of an effective amount of potentiated magnesium, and when administered in…effective dosages balances calcium metabolism, [and] maintains the homeostasis of the cardiovascular system…in the human body.”

U.S. Patent No. 6,372,264 abstract (in part):

“A method for reducing…cellular malfunction with the administration of…effective dosages of a compounded coordination complex of magnesium.  The method includes steps for making and administering a compounded coordination complex…[and] A standardized method for making a compounded coordination complex of inorganic minerals is also disclosed.”

The worldwide patents that cover Potentiated Magnesium (pMg) are some of the most extraordinary patents ever issued, especially considering the impact that pMg is likely to have in the coming years in supporting natural health – especially heart health – and increasing the human Health Span.  Natural heart health and slowing the aging process:  It probably doesn’t get much better than that.

The Trademarks

The registered trademarks owned by Maxcelint Laboratories Inc. (MLI) include: Potentiated, Potentiated Magnesium, pMg, Go To The MAX, Maxcelint and Maxcelint Uptake.  Other MLI trademarks include: Compound Complex, Maximum Excellence, Supercharged Synergy, The Five Pillars of Health, The Complete Nutrient Directory, Nutrients-At-A-Glance, The Advanced Glycemic Index, Stress & Tension Alleviating Response (STAR), Get to The Heart of The Matter, Be Young at Heart with pMg, Be MAX Strong, Youthful Vitality Forged From Nature’s Strength, Home Is Where The Heart Is, The Tree with Swing Logo, The Red Heart Logo, The Dumbbell with “X” Logo, The Starburst Logo, The Leaf Logo, The Best of Mother Nature blended with modern science, and the Laboratory Certified Seal.  All words and items that have a registered trademark symbol ® or a trademark symbol ™ are the exclusive Intellectual Property of Maxcelint Laboratories Inc.  All rights are reserved.

The Copyrights

The entire content of this Website is copyrighted each year by Maxcelint Laboratories Inc. Printed product materials, the entire label of pMg – Potentiated Magnesium, and the entire label of Go To The MAX – Potentiated Magnesium plus Zinc, have been copyrighted every year, beginning in 2007, by Maxcelint Laboratories Inc. All rights are reserved.

All Intellectual Property indicated (patents, trademarks and copyrights) are the exclusive property of Maxcelint Laboratories Inc. All rights are reserved.

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